HBV Target gene Detail Information

> NSMCE2 Gene Search Result

Gene Information

Gene Name	NSMCE2
Gene ID	286053
Gene Full Name	NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
Gene Alias	NSE2; MMS21; ZMIZ7; C8orf36
Transcripts	ENSG00000156831
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q96MF7
HGNC ID	HGNC:26513
VEGA ID	OTTHUMG00000164993
OMIM ID	617246
String ID	9606.ENSP00000287437
PharmGKB ID	PA142672355

Target gene [NSMCE2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1008902	chr8	17	1		18	View
1403357	chr8	17	1		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NSMCE2 expression and immune infiltrating cell level correlation result in HBV+ samples
NSMCE2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).