HIV Target gene Detail Information

> NSMAF Gene Search Result

Gene Information

Gene Name	NSMAF
Gene ID	8439
Gene Full Name	neutral sphingomyelinase activation associated factor
Gene Alias	FAN; GRAMD5
Transcripts	ENSG00000035681
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q92636
HGNC ID	HGNC:8017
VEGA ID	OTTHUMG00000164352
OMIM ID	603043
String ID	9606.ENSP00000411012
PharmGKB ID	PA31795

Target gene [NSMAF] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005079	chr8	15	10	11	36	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NSMAF expression and immune infiltrating cell level correlation result in HIV+ samples
NSMAF expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NSMAF expression and immune infiltrating cell level correlation result in HIV+ samples
NSMAF expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).