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HIV Target gene Detail Information

> NSD1 Gene Search Result


Gene Information
Gene Name NSD1
Gene ID 64324
Gene Full Name nuclear receptor binding SET domain protein 1
Gene Alias STO; KMT3B; SOTOS; ARA267; SOTOS1
Transcripts ENSG00000165671
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Plasma membrane;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q96L73
HGNC ID HGNC:14234
VEGA ID OTTHUMG00000130846
OMIM ID 606681
String ID 9606.ENSP00000395929
PharmGKB ID PA31790
Target gene [NSD1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000114 chr5 60 423 534 1017 View
4000115 chr5 58 422 534 1014 View
4000735 chr5 298 1 299 View
4002053 chr5 102 13 115 View
4003728 chr5 53 3 56 View
4004074 chr5 49 1 50 View
4004382 chr5 8 37 45 View
4005835 chr5 24 5 29 View
4006761 chr5 8 14 1 23 View
4007211 chr5 10 10 20 View
4007275 chr5 19 1 20 View
4007829 chr5 15 2 17 View
4008028 chr5 14 3 17 View
4008565 chr5 13 1 14 View
4008974 chr5 10 3 13 View
4009041 chr5 12 1 13 View
4010804 chr5 8 8 View
4011480 chr5 6 1 7 View
4011481 chr5 6 1 7 View
4012333 chr5 5 5 View
4012334 chr5 5 5 View
4016385 chr5 0 View
4016531 chr5 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NSD1 expression and immune infiltrating cell level correlation result in HIV+ samples
NSD1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NSD1 expression and immune infiltrating cell level correlation result in HIV+ samples
NSD1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).