HBV Target gene Detail Information

> NRXN1 Gene Search Result

Gene Information

Gene Name	NRXN1
Gene ID	9378
Gene Full Name	neurexin 1
Gene Alias	PTHSL2; SCZD17; Hs.22998
Transcripts	ENSG00000179915
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	P58400; Q9ULB1
HGNC ID	HGNC:8008
VEGA ID	OTTHUMG00000129263
OMIM ID	600565
String ID	9606.ENSP00000385142
Drugbank ID	BE0005199; BE0005274
PharmGKB ID	PA31786

Target gene [NRXN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1014281	chr2		4		4	View
1014438	chr2		3		3	View
1014439	chr2		3		3	View
1016068	chr2		1	1	2	View
1016484	chr2		1		1	View
1019620	chr2				0	View
1400046	chr2	1	1		2	View
1402719	chr2		3		3	View
1402720	chr2		3		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NRXN1 expression and immune infiltrating cell level correlation result in HBV+ samples
NRXN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).