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HTLV1 Target gene Detail Information

> NRAP Gene Search Result


Gene Information
Gene Name NRAP
Gene ID 4892
Gene Full Name nebulin related anchoring protein
Gene Alias N-RAP
Transcripts ENSG00000197893
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q86VF7
HGNC ID HGNC:7988
VEGA ID OTTHUMG00000019072
OMIM ID 602873
String ID 9606.ENSP00000358365
PharmGKB ID PA31767
Target gene [NRAP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6009043 chr10 27 13 40 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of NRAP expression and immune infiltrating cell level correlation result in HTLV1+ samples
NRAP expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of NRAP expression and immune infiltrating cell level correlation result in HTLV1+ samples
NRAP expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of NRAP expression and immune infiltrating cell level correlation result in HTLV1+ samples
NRAP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).