HBV Target gene Detail Information

> NR2C2 Gene Search Result

Gene Information

Gene Name	NR2C2
Gene ID	7182
Gene Full Name	nuclear receptor subfamily 2 group C member 2
Gene Alias	TR4; TAK1
Transcripts	ENSG00000177463
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	P49116
HGNC ID	HGNC:7972
VEGA ID	OTTHUMG00000129839
OMIM ID	601426
String ID	9606.ENSP00000483059
PharmGKB ID	PA31755

Target gene [NR2C2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004442	chr3	68	11	2	81	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NR2C2 expression and immune infiltrating cell level correlation result in HBV+ samples
NR2C2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).