HBV Target gene Detail Information

> NR2C1 Gene Search Result


Gene Information
Gene Name NR2C1
Gene ID 7181
Gene Full Name nuclear receptor subfamily 2 group C member 1
Gene Alias TR2
Transcripts ENSG00000120798
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cell Junctions;Cytosol;
HPA Protein Class Info Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID P13056
HGNC ID HGNC:7971
VEGA ID OTTHUMG00000170131
OMIM ID 601529
String ID 9606.ENSP00000333275
PharmGKB ID PA31754
Target gene [NR2C1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009894 chr12 13 1 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NR2C1 expression and immune infiltrating cell level correlation result in HBV+ samples
NR2C1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).