HBV Target gene Detail Information

> NR1H3 Gene Search Result

Gene Information

Gene Name	NR1H3
Gene ID	10062
Gene Full Name	nuclear receptor subfamily 1 group H member 3
Gene Alias	LXRA; LXR-a; RLD-1
Transcripts	ENSG00000025434
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q13133
HGNC ID	HGNC:7966
VEGA ID	OTTHUMG00000150628
OMIM ID	602423
String ID	9606.ENSP00000477707
Drugbank ID	BE0003781
PharmGKB ID	PA31751

Target gene [NR1H3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1404691	chr11	108	35	210	353	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NR1H3 expression and immune infiltrating cell level correlation result in HBV+ samples
NR1H3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).