HBV Target gene Detail Information

> NR1D2 Gene Search Result

Gene Information

Gene Name	NR1D2
Gene ID	9975
Gene Full Name	nuclear receptor subfamily 1 group D member 2
Gene Alias	RVR; BD73; EAR-1R; REVERBB; REVERBbeta
Transcripts	ENSG00000174738
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Nuclear receptors, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q14995
HGNC ID	HGNC:7963
VEGA ID	OTTHUMG00000155659
OMIM ID	602304
String ID	9606.ENSP00000310006
Drugbank ID	BE0009311
PharmGKB ID	PA31749

Target gene [NR1D2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001711	chr3	221	209	90	520	View
1004451	chr3	78	2	1	81	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NR1D2 expression and immune infiltrating cell level correlation result in HBV+ samples
NR1D2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).