HIV Target gene Detail Information

> NPTN Gene Search Result

Gene Information

Gene Name	NPTN
Gene ID	27020
Gene Full Name	neuroplastin
Gene Alias	GP55; GP65; SDR1; np55; np65; SDFR1
Transcripts	ENSG00000156642
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y639
HGNC ID	HGNC:17867
VEGA ID	OTTHUMG00000137586
OMIM ID	612820
String ID	9606.ENSP00000290401
PharmGKB ID	PA134927704

Target gene [NPTN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001630	chr15	54	48	43	145	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NPTN expression and immune infiltrating cell level correlation result in HIV+ samples
NPTN expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NPTN expression and immune infiltrating cell level correlation result in HIV+ samples
NPTN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).