HIV Target gene Detail Information

> NPLOC4 Gene Search Result

Gene Information

Gene Name	NPLOC4
Gene ID	55666
Gene Full Name	NPL4 homolog, ubiquitin recognition factor
Gene Alias	NPL4
Transcripts	ENSG00000182446
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins, Transporters
Uniport_ID	Q8TAT6
HGNC ID	HGNC:18261
VEGA ID	OTTHUMG00000177990
OMIM ID	606590
String ID	9606.ENSP00000331487
PharmGKB ID	PA143485558

Target gene [NPLOC4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000317	chr17	486	43	21	550	View
4000791	chr17	273	7		280	View
4002938	chr17	72	2		74	View
4002939	chr17	72	2		74	View
4003286	chr17	58	5	1	64	View
4003807	chr17	25	29		54	View
4004707	chr17	33	7		40	View
4006309	chr17	19	2	4	25	View
4006876	chr17	19	3		22	View
4007878	chr17	16	1		17	View
4011135	chr17	4	3		7	View
4011220	chr17	4	3		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NPLOC4 expression and immune infiltrating cell level correlation result in HIV+ samples
NPLOC4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NPLOC4 expression and immune infiltrating cell level correlation result in HIV+ samples
NPLOC4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).