HBV Target gene Detail Information

> NPHS1 Gene Search Result

Gene Information

Gene Name	NPHS1
Gene ID	4868
Gene Full Name	NPHS1, nephrin
Gene Alias	CNF; NPHN; nephrin
Transcripts	ENSG00000161270
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O60500
HGNC ID	HGNC:7908
VEGA ID	OTTHUMG00000180689
OMIM ID	602716
String ID	9606.ENSP00000368190
PharmGKB ID	PA31709

Target gene [NPHS1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001682	chr19	475	52		527	View
1012576	chr19	2	4		6	View
1401046	chr19	2	4		6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NPHS1 expression and immune infiltrating cell level correlation result in HBV+ samples
NPHS1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).