HIV Target gene Detail Information

> NPHP4 Gene Search Result

Gene Information

Gene Name	NPHP4
Gene ID	261734
Gene Full Name	nephrocystin 4
Gene Alias	POC10; SLSN4
Transcripts	ENSG00000131697
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;Nuclear bodies;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75161
HGNC ID	HGNC:19104
VEGA ID	OTTHUMG00000000701
OMIM ID	607215
String ID	9606.ENSP00000367398
PharmGKB ID	PA134927048

Target gene [NPHP4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001122	chr1	89	54	67	210	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NPHP4 expression and immune infiltrating cell level correlation result in HIV+ samples
NPHP4 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NPHP4 expression and immune infiltrating cell level correlation result in HIV+ samples
NPHP4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).