HBV Target gene Detail Information

> NPFFR2 Gene Search Result


Gene Information
Gene Name NPFFR2
Gene ID 10886
Gene Full Name neuropeptide FF receptor 2
Gene Alias GPR74; NPFF2; NPGPR; HLWAR77
Transcripts ENSG00000056291
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Actin filaments;
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9Y5X5
HGNC ID HGNC:4525
VEGA ID OTTHUMG00000129918
OMIM ID 607449
String ID 9606.ENSP00000307822
PharmGKB ID PA28918
Target gene [NPFFR2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1400010 chr4 0 View
1400036 chr4 2 1 3 View
1400037 chr4 0 View
1400038 chr4 3 47 6 56 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NPFFR2 expression and immune infiltrating cell level correlation result in HBV+ samples
NPFFR2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).