HBV Target gene Detail Information

> NPFFR2 Gene Search Result

Gene Information

Gene Name	NPFFR2
Gene ID	10886
Gene Full Name	neuropeptide FF receptor 2
Gene Alias	GPR74; NPFF2; NPGPR; HLWAR77
Transcripts	ENSG00000056291
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Actin filaments;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9Y5X5
HGNC ID	HGNC:4525
VEGA ID	OTTHUMG00000129918
OMIM ID	607449
String ID	9606.ENSP00000307822
PharmGKB ID	PA28918

Target gene [NPFFR2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1400010	chr4				0	View
1400036	chr4	2	1		3	View
1400037	chr4				0	View
1400038	chr4	3	47	6	56	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NPFFR2 expression and immune infiltrating cell level correlation result in HBV+ samples
NPFFR2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).