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HTLV1 Target gene Detail Information

> NPAS4 Gene Search Result


Gene Information
Gene Name NPAS4
Gene ID 266743
Gene Full Name neuronal PAS domain protein 4
Gene Alias NXF; Le-PAS; PASD10; bHLHe79
Transcripts ENSG00000174576
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q8IUM7
HGNC ID HGNC:18983
VEGA ID OTTHUMG00000167045
OMIM ID 608554
String ID 9606.ENSP00000311196
PharmGKB ID PA142671254
Target gene [NPAS4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000510 chr11 279 589 503 1371 View
6001056 chr11 502 63 51 616 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of NPAS4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NPAS4 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of NPAS4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NPAS4 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of NPAS4 expression and immune infiltrating cell level correlation result in HTLV1+ samples
NPAS4 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).