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HIV Target gene Detail Information

> NOSIP Gene Search Result


Gene Information
Gene Name NOSIP
Gene ID 51070
Gene Full Name nitric oxide synthase interacting protein
Gene Alias CGI-25
Transcripts ENSG00000142546
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9Y314
HGNC ID HGNC:17946
VEGA ID OTTHUMG00000183169
OMIM ID 616759
String ID 9606.ENSP00000470034
PharmGKB ID PA134989259
Target gene [NOSIP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000866 chr19 151 60 51 262 View
4001649 chr19 141 2 1 144 View
4001650 chr19 141 2 1 144 View
4001915 chr19 70 25 28 123 View
4002035 chr19 87 20 9 116 View
4003574 chr19 49 9 58 View
4008774 chr19 8 5 1 14 View
4009464 chr19 7 3 1 11 View
4009465 chr19 10 1 11 View
4009747 chr19 4 7 11 View
4009943 chr19 4 6 10 View
4010723 chr19 7 1 8 View
4011599 chr19 5 1 6 View
4011600 chr19 5 1 6 View
4012277 chr19 4 1 5 View
4014188 chr19 1 1 2 View
4014189 chr19 1 1 2 View
4014415 chr19 2 2 View
4016273 chr19 0 View
4016622 chr19 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NOSIP expression and immune infiltrating cell level correlation result in HIV+ samples
NOSIP expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NOSIP expression and immune infiltrating cell level correlation result in HIV+ samples
NOSIP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).