HIV Target gene Detail Information

> NOP2 Gene Search Result


Gene Information
Gene Name NOP2
Gene ID 4839
Gene Full Name NOP2 nucleolar protein
Gene Alias NOL1; p120; NSUN1; NOP120
Transcripts ENSG00000111641
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoli;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID P46087
HGNC ID HGNC:7867
VEGA ID OTTHUMG00000169163
OMIM ID 164031
String ID 9606.ENSP00000371858
PharmGKB ID PA164724026
Target gene [NOP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002303 chr12 18 82 100 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NOP2 expression and immune infiltrating cell level correlation result in HIV+ samples
NOP2 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NOP2 expression and immune infiltrating cell level correlation result in HIV+ samples
NOP2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).