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HBV Target gene Detail Information

> NMT1 Gene Search Result


Gene Information
Gene Name NMT1
Gene ID 4836
Gene Full Name N-myristoyltransferase 1
Gene Alias NMT
Transcripts ENSG00000136448
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P30419
HGNC ID HGNC:7857
VEGA ID OTTHUMG00000180003
OMIM ID 160993
String ID 9606.ENSP00000468424
Drugbank ID BE0001502; BE0004329
PharmGKB ID PA31661
Target gene [NMT1] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 27132039 G1764A
BCP
G
 View

Target gene [NMT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005587 chr17 49 2 51 View
1007366 chr19 15 13 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of NMT1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
NMT1 expression: Low -> High
Lollipop of NMT1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of NMT1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NMT1 expression and immune infiltrating cell level correlation result in HBV+ samples
NMT1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).