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HIV Target gene Detail Information

> NLK Gene Search Result


Gene Information
Gene Name NLK
Gene ID 51701
Gene Full Name nemo like kinase
Transcripts ENSG00000087095
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cell Junctions;Nucleoli;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID Q9UBE8
HGNC ID HGNC:29858
VEGA ID OTTHUMG00000132451
OMIM ID 609476
String ID 9606.ENSP00000384625
PharmGKB ID PA134914500
Target gene [NLK] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002533 chr17 69 13 8 90 View
4003726 chr17 28 9 19 56 View
4005978 chr17 24 4 28 View
4007554 chr17 18 1 19 View
4008535 chr17 9 6 15 View
4009929 chr17 5 4 1 10 View
4011712 chr17 6 6 View
4014709 chr17 2 2 View
4015630 chr17 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NLK expression and immune infiltrating cell level correlation result in HIV+ samples
NLK expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of NLK expression and immune infiltrating cell level correlation result in HIV+ samples
NLK expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).