HPV Target gene Detail Information

> NKX1-1 Gene Search Result

Gene Information

Gene Name	NKX1-1
Gene ID	54729
Gene Full Name	NK1 homeobox 1
Gene Alias	SAX2; HSPX153; NKX-1.1
Transcripts	ENSG00000235608
Virus	HPV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoli fibrillar center;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q15270
HGNC ID	HGNC:24975
VEGA ID	OTTHUMG00000160165
OMIM ID	617869
String ID	9606.ENSP00000407978
PharmGKB ID	PA145148380

Target gene [NKX1-1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5403671	chr4	25			25	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE140662 (GEO)	Condyloma Acuminatum	8	Condyloma acuminata (HPV+)(5), Skin(3)
GSE51993 (GEO)	Cervical intraepithelial neoplasia	24	Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)

> Dataset: GSE140662
HeatMap of cell type fractions in all samples	Lollipop of NKX1-1 expression and immune infiltrating cell level correlation result in HPV+ samples
NKX1-1 expression: Low -> High

> Dataset: GSE51993
HeatMap of cell type fractions in all samples	Lollipop of NKX1-1 expression and immune infiltrating cell level correlation result in HPV+ samples
NKX1-1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).