HBV Target gene Detail Information

> NKAIN2 Gene Search Result

Gene Information

Gene Name	NKAIN2
Gene ID	154215
Gene Full Name	sodium/potassium transporting ATPase interacting 2
Gene Alias	TCBA; TCBA1; FAM77B; NKAIP2
Transcripts	ENSG00000188580
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Uniport_ID	Q5VXU1
HGNC ID	HGNC:16443
VEGA ID	OTTHUMG00000015500
OMIM ID	609758
String ID	9606.ENSP00000357402
PharmGKB ID	PA162397563

Target gene [NKAIN2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004256	chr6	1	61	25	87	View
1006613	chr6	28	1	7	36	View
1011050	chr6	1		9	10	View
1011782	chr6	1		7	8	View
1013114	chr6	5			5	View
1014495	chr6	3			3	View
1019354	chr6				0	View
1019642	chr6				0	View
1401182	chr6	3			3	View
1402166	chr6	5			5	View
1404408	chr6	9	1		10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NKAIN2 expression and immune infiltrating cell level correlation result in HBV+ samples
NKAIN2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).