HIV Target gene Detail Information

> NIN Gene Search Result

Gene Information

Gene Name	NIN
Gene ID	51199
Gene Full Name	ninein
Gene Alias	SCKL7
Transcripts	ENSG00000100503
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centrosome;Nucleoli;Nucleoli rim;Nucleoplasm;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8N4C6
HGNC ID	HGNC:14906
VEGA ID	OTTHUMG00000029569
OMIM ID	608684
String ID	9606.ENSP00000371472
PharmGKB ID	PA31630

Target gene [NIN] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000228	chr14	144	195	353	692	View
4008404	chr14	3	11	1	15	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NIN expression and immune infiltrating cell level correlation result in HIV+ samples
NIN expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NIN expression and immune infiltrating cell level correlation result in HIV+ samples
NIN expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).