HBV Target gene Detail Information

> NFYC Gene Search Result


Gene Information
Gene Name NFYC
Gene ID 4802
Gene Full Name nuclear transcription factor Y subunit gamma
Gene Alias HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A
Transcripts ENSG00000066136
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q13952
HGNC ID HGNC:7806
VEGA ID OTTHUMG00000007729
OMIM ID 605344
String ID 9606.ENSP00000396620
PharmGKB ID PA31611
Target gene [NFYC] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002011 chr1 70 238 68 376 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NFYC expression and immune infiltrating cell level correlation result in HBV+ samples
NFYC expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).