HBV Target gene Detail Information

> NFX1 Gene Search Result


Gene Information
Gene Name NFX1
Gene ID 4799
Gene Full Name nuclear transcription factor, X-box binding 1
Gene Alias NFX2; Tex42; TEG-42
Transcripts ENSG00000086102
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q12986
HGNC ID HGNC:7803
VEGA ID OTTHUMG00000019772
OMIM ID 603255
String ID 9606.ENSP00000368856
PharmGKB ID PA31608
Target gene [NFX1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011755 chr9 4 4 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NFX1 expression and immune infiltrating cell level correlation result in HBV+ samples
NFX1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).