HIV Target gene Detail Information

> NFIL3 Gene Search Result

Gene Information

Gene Name	NFIL3
Gene ID	4783
Gene Full Name	nuclear factor, interleukin 3 regulated
Gene Alias	E4BP4; IL3BP1; NFIL3A; NF-IL3A
Transcripts	ENSG00000165030
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	Q16649
HGNC ID	HGNC:7787
VEGA ID	OTTHUMG00000020209
OMIM ID	605327
String ID	9606.ENSP00000297689
PharmGKB ID	PA31593

Target gene [NFIL3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007027	chr9	21			21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NFIL3 expression and immune infiltrating cell level correlation result in HIV+ samples
NFIL3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NFIL3 expression and immune infiltrating cell level correlation result in HIV+ samples
NFIL3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).