HIV Target gene Detail Information

> NFE2L3 Gene Search Result

Gene Information

Gene Name	NFE2L3
Gene ID	9603
Gene Full Name	nuclear factor, erythroid 2 like 3
Gene Alias	NRF3
Transcripts	ENSG00000050344
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q9Y4A8
HGNC ID	HGNC:7783
VEGA ID	OTTHUMG00000023882
OMIM ID	604135
String ID	9606.ENSP00000056233
PharmGKB ID	PA31589

Target gene [NFE2L3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008717	chr7	13	1		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NFE2L3 expression and immune infiltrating cell level correlation result in HIV+ samples
NFE2L3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NFE2L3 expression and immune infiltrating cell level correlation result in HIV+ samples
NFE2L3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).