HBV Target gene Detail Information

> NFATC3 Gene Search Result


Gene Information
Gene Name NFATC3
Gene ID 4775
Gene Full Name nuclear factor of activated T cells 3
Gene Alias NFAT4; NFATX
Transcripts ENSG00000072736
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins, Transcription factors
Uniport_ID Q12968
HGNC ID HGNC:7777
VEGA ID OTTHUMG00000137555
OMIM ID 602698
String ID 9606.ENSP00000300659
PharmGKB ID PA247
Target gene [NFATC3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002626 chr16 63 77 96 236 View
1010489 chr16 11 1 12 View
1400356 chr16 2613 329 120 3062 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NFATC3 expression and immune infiltrating cell level correlation result in HBV+ samples
NFATC3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).