HBV Target gene Detail Information

> NFAT5 Gene Search Result

Gene Information

Gene Name	NFAT5
Gene ID	10725
Gene Full Name	nuclear factor of activated T cells 5
Gene Alias	NFATZ; OREBP; NF-AT5; NFATL1; TONEBP
Transcripts	ENSG00000102908
Virus	HBV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Uniport_ID	O94916
HGNC ID	HGNC:7774
VEGA ID	OTTHUMG00000137572
OMIM ID	604708
String ID	9606.ENSP00000457593
PharmGKB ID	PA31581

Target gene [NFAT5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1004958	chr16	3	13	49	65	View
1005654	chr16	50			50	View
1008361	chr16	18	3		21	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NFAT5 expression and immune infiltrating cell level correlation result in HBV+ samples
NFAT5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).