HIV Target gene Detail Information

> NEIL3 Gene Search Result

Gene Information

Gene Name	NEIL3
Gene ID	55247
Gene Full Name	nei like DNA glycosylase 3
Gene Alias	FGP2; FPG2; NEI3; ZGRF3; hFPG2; hNEI3
Transcripts	ENSG00000109674
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8TAT5
HGNC ID	HGNC:24573
VEGA ID	OTTHUMG00000160722
OMIM ID	608934
String ID	9606.ENSP00000264596
PharmGKB ID	PA134889634

Target gene [NEIL3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001148	chr4	109	16	78	203	View
4002679	chr4	76	7		83	View
4005717	chr4	30			30	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NEIL3 expression and immune infiltrating cell level correlation result in HIV+ samples
NEIL3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).