HBV Target gene Detail Information

> NEGR1 Gene Search Result

Gene Information

Gene Name	NEGR1
Gene ID	257194
Gene Full Name	neuronal growth regulator 1
Gene Alias	Ntra; KILON; IGLON4; DMML2433
Transcripts	ENSG00000172260
Virus	HBV
Gene Type	protein coding
HPA Location Info	Actin filaments;Cytosol;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	Q7Z3B1
HGNC ID	HGNC:17302
VEGA ID	OTTHUMG00000009698
OMIM ID	613173
String ID	9606.ENSP00000350364
PharmGKB ID	PA134862452

Target gene [NEGR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1016088	chr1	2			2	View
1017440	chr1	1			1	View
1400362	chr1				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NEGR1 expression and immune infiltrating cell level correlation result in HBV+ samples
NEGR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).