HBV Target gene Detail Information

> NECAB1 Gene Search Result


Gene Information
Gene Name NECAB1
Gene ID 64168
Gene Full Name N-terminal EF-hand calcium binding protein 1
Gene Alias EFCBP1; STIP-1
Transcripts ENSG00000123119
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q8N987
HGNC ID HGNC:20983
VEGA ID OTTHUMG00000164009
String ID 9606.ENSP00000387380
PharmGKB ID PA162397411
Target gene [NECAB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006813 chr8 21 12 1 34 View
1010031 chr8 3 4 6 13 View
1014382 chr8 2 1 3 View
1402497 chr8 2 1 3 View
1403125 chr8 3 4 6 13 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NECAB1 expression and immune infiltrating cell level correlation result in HBV+ samples
NECAB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).