HBV Target gene Detail Information

> NDUFS1 Gene Search Result


Gene Information
Gene Name NDUFS1
Gene ID 4719
Gene Full Name NADH:ubiquinone oxidoreductase core subunit S1
Gene Alias CI-75k; CI-75Kd; PRO1304
Transcripts ENSG00000283447
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P28331
HGNC ID HGNC:7707
VEGA ID OTTHUMG00000132892
OMIM ID 157655
String ID 9606.ENSP00000392709
Drugbank ID BE0000493
PharmGKB ID PA31518
Target gene [NDUFS1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1011113 chr2 6 4 10 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NDUFS1 expression and immune infiltrating cell level correlation result in HBV+ samples
NDUFS1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).