HBV Target gene Detail Information

> NDUFA4 Gene Search Result

Gene Information

Gene Name	NDUFA4
Gene ID	4697
Gene Full Name	NDUFA4, mitochondrial complex associated
Gene Alias	MLRQ; CI-9k; COXFA4; CI-MLRQ
Transcripts	ENSG00000189043
Virus	HBV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	O00483
HGNC ID	HGNC:7687
VEGA ID	OTTHUMG00000023880
OMIM ID	603833
String ID	9606.ENSP00000339720
Drugbank ID	BE0000169
PharmGKB ID	PA31493

Target gene [NDUFA4] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1013519	chr7		5		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NDUFA4 expression and immune infiltrating cell level correlation result in HBV+ samples
NDUFA4 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).