HBV Target gene Detail Information

> NDST1 Gene Search Result

Gene Information

Gene Name	NDST1
Gene ID	3340
Gene Full Name	N-deacetylase and N-sulfotransferase 1
Gene Alias	HSST; NST1; MRT46
Transcripts	ENSG00000070614
Virus	HBV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P52848
HGNC ID	HGNC:7680
VEGA ID	OTTHUMG00000163572
OMIM ID	600853
String ID	9606.ENSP00000261797
Drugbank ID	BE0002559
PharmGKB ID	PA31486

Target gene [NDST1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1001951	chr5	9	187	208	404	View
1001973	chr5	10	183	196	389	View
1002025	chr5	35	236	100	371	View
1002080	chr5	35	222	95	352	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE114783 (GEO)	Chronic HBV (CHB) infection	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Hepatocellular carcinoma	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO)	Liver cirrhosis	36	Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783
HeatMap of cell type fractions in all samples	Lollipop of NDST1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
NDST1 expression: Low -> High
Lollipop of NDST1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples	Lollipop of NDST1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples


> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NDST1 expression and immune infiltrating cell level correlation result in HBV+ samples
NDST1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).