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HBV Target gene Detail Information

> NCOR2 Gene Search Result


Gene Information
Gene Name NCOR2
Gene ID 9612
Gene Full Name nuclear receptor corepressor 2
Gene Alias SMRT; TRAC; CTG26; SMRTE; TRAC1; N-CoR2; TNRC14; TRAC-1; SMAP270; SMRTE-tau
Transcripts ENSG00000196498
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID Q9Y618
HGNC ID HGNC:7673
VEGA ID OTTHUMG00000150455
OMIM ID 600848
String ID 9606.ENSP00000384018
PharmGKB ID PA31478
Target gene [NCOR2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001611 chr12 109 225 279 613 View
1001803 chr12 49 165 266 480 View
1002441 chr12 48 78 147 273 View
1002458 chr12 248 23 271 View
1002656 chr12 10 73 146 229 View
1400506 chr12 15 4 19 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of NCOR2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
NCOR2 expression: Low -> High
Lollipop of NCOR2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of NCOR2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of NCOR2 expression and immune infiltrating cell level correlation result in HBV+ samples
NCOR2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).