HIV Target gene Detail Information

> NCOA7 Gene Search Result

Gene Information

Gene Name	NCOA7
Gene ID	135112
Gene Full Name	nuclear receptor coactivator 7
Gene Alias	ESNA1; TLDC4; ERAP140; NCOA7-AS; Nbla00052; Nbla10993; dJ187J11.3
Transcripts	ENSG00000111912
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear bodies;Nucleoplasm;Golgi apparatus;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q8NI08
HGNC ID	HGNC:21081
VEGA ID	OTTHUMG00000015513
OMIM ID	609752
String ID	9606.ENSP00000376269
PharmGKB ID	PA134905581

Target gene [NCOA7] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003282	chr6	59	5	1	65	View
4003995	chr6	48	3		51	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of NCOA7 expression and immune infiltrating cell level correlation result in HIV+ samples
NCOA7 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of NCOA7 expression and immune infiltrating cell level correlation result in HIV+ samples
NCOA7 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).