HBV Target gene Detail Information

> NCKAP1 Gene Search Result

Gene Information

Gene Name	NCKAP1
Gene ID	10787
Gene Full Name	NCK associated protein 1
Gene Alias	HEM2; NAP1; NAP125; p125Nap1
Transcripts	ENSG00000061676
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9Y2A7
HGNC ID	HGNC:7666
VEGA ID	OTTHUMG00000132623
OMIM ID	604891
String ID	9606.ENSP00000354251
PharmGKB ID	PA31468

Target gene [NCKAP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1015475	chr2	2			2	View
1404947	chr2	4	4		8	View
1405005	chr2	27	1		28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of NCKAP1 expression and immune infiltrating cell level correlation result in HBV+ samples
NCKAP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).