HIV Target gene Detail Information

> NBR1 Gene Search Result


Gene Information
Gene Name NBR1
Gene ID 4077
Gene Full Name NBR1, autophagy cargo receptor
Gene Alias IAI3B; M17S2; MIG19; 1A1-3B
Transcripts ENSG00000188554
Virus HIV
Gene Type protein coding
HPA Location Info Vesicles;Nuclear bodies;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q14596
HGNC ID HGNC:6746
VEGA ID OTTHUMG00000180878
OMIM ID 166945
String ID 9606.ENSP00000411250
PharmGKB ID PA30510
Target gene [NBR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4003234 chr17 63 3 66 View
4006334 chr17 24 1 25 View
4007613 chr17 15 2 1 18 View
4015752 chr17 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of NBR1 expression and immune infiltrating cell level correlation result in HIV+ samples
NBR1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).