HBV Target gene Detail Information

> N4BP2L2 Gene Search Result


Gene Information
Gene Name N4BP2L2
Gene ID 10443
Gene Full Name NEDD4 binding protein 2 like 2
Gene Alias CG005; CG016; PFAAP5; 92M18.3
Transcripts ENSG00000244754
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q92802
HGNC ID HGNC:26916
VEGA ID OTTHUMG00000016700
OMIM ID 615788
String ID 9606.ENSP00000382328
PharmGKB ID PA162396632
Target gene [N4BP2L2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007339 chr13 25 3 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of N4BP2L2 expression and immune infiltrating cell level correlation result in HBV+ samples
N4BP2L2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).