HBV Target gene Detail Information

> MYOCD Gene Search Result


Gene Information
Gene Name MYOCD
Gene ID 93649
Gene Full Name myocardin
Gene Alias MYCD
Transcripts ENSG00000141052
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID Q8IZQ8
HGNC ID HGNC:16067
VEGA ID OTTHUMG00000058767
OMIM ID 606127
String ID 9606.ENSP00000401678
PharmGKB ID PA134946896
Target gene [MYOCD] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1013763 chr17 3 1 4 View
1018024 chr17 0 View
1400659 chr17 0 View
1401682 chr17 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MYOCD expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MYOCD expression: Low -> High
Lollipop of MYOCD expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MYOCD expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MYOCD expression and immune infiltrating cell level correlation result in HBV+ samples
MYOCD expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).