HIV Target gene Detail Information

> MYO5A Gene Search Result

Gene Information

Gene Name	MYO5A
Gene ID	4644
Gene Full Name	myosin VA
Gene Alias	GS1; MYO5; MYH12; MYR12
Transcripts	ENSG00000197535
Virus	HIV
Gene Type	protein coding
HPA Location Info	Centriolar satellite;Focal adhesion sites;
HPA Protein Class Info	Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y4I1
HGNC ID	HGNC:7602
VEGA ID	OTTHUMG00000137383
OMIM ID	160777
String ID	9606.ENSP00000382177
PharmGKB ID	PA31407

Target gene [MYO5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001638	chr15	29	52	64	145	View
4007660	chr15	3	15		18	View
4010948	chr15	8			8	View
4015970	chr15				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MYO5A expression and immune infiltrating cell level correlation result in HIV+ samples
MYO5A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MYO5A expression and immune infiltrating cell level correlation result in HIV+ samples
MYO5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).