HIV Target gene Detail Information

> MYL6B Gene Search Result

Gene Information

Gene Name	MYL6B
Gene ID	140465
Gene Full Name	myosin light chain 6B
Gene Alias	MLC1SA
Transcripts	ENSG00000196465
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	P14649
HGNC ID	HGNC:29823
VEGA ID	OTTHUMG00000170199
OMIM ID	609930
String ID	9606.ENSP00000450385
Drugbank ID	BE0004292
PharmGKB ID	PA144596407

Target gene [MYL6B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002443	chr12	85	5	4	94	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MYL6B expression and immune infiltrating cell level correlation result in HIV+ samples
MYL6B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MYL6B expression and immune infiltrating cell level correlation result in HIV+ samples
MYL6B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).