HTLV1 Target gene Detail Information

> MYH11 Gene Search Result


Gene Information
Gene Name MYH11
Gene ID 4629
Gene Full Name myosin heavy chain 11
Gene Alias AAT4; FAA4; SMHC; SMMHC
Transcripts ENSG00000276480
Virus HTLV1
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P35749
HGNC ID HGNC:7569
VEGA ID OTTHUMG00000191107
OMIM ID 160745
String ID 9606.ENSP00000379616
Drugbank ID BE0004489
PharmGKB ID PA31367
Target gene [MYH11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6016921 chr16 11 11 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of MYH11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MYH11 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of MYH11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MYH11 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of MYH11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MYH11 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).