HIV Target gene Detail Information

> MYB Gene Search Result

Gene Information

Gene Name	MYB
Gene ID	4602
Gene Full Name	MYB proto-oncogene, transcription factor
Gene Alias	efg; Cmyb; c-myb; c-myb_CDS
Transcripts	ENSG00000118513
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transcription factors
Gene Function	Oncogene
Uniport_ID	P10242
HGNC ID	HGNC:7545
VEGA ID	OTTHUMG00000015629
OMIM ID	189990
String ID	9606.ENSP00000339992
PharmGKB ID	PA31345

Target gene [MYB] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002648	chr6	57	15	13	85	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MYB expression and immune infiltrating cell level correlation result in HIV+ samples
MYB expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MYB expression and immune infiltrating cell level correlation result in HIV+ samples
MYB expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).