HBV Target gene Detail Information

> MX1 Gene Search Result

Gene Information

Gene Name	MX1
Gene ID	4599
Gene Full Name	MX dynamin like GTPase 1
Gene Alias	MX; MxA; IFI78; IFI-78K
Transcripts	ENSG00000157601
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Nuclear membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	P20591
HGNC ID	HGNC:7532
VEGA ID	OTTHUMG00000086755
OMIM ID	147150
String ID	9606.ENSP00000381601
PharmGKB ID	PA31333

Target gene [MX1] related to virus gene/protein/region

ID	PMID	Mutation	Gene/Protein/Region	Description	Detail
1	20959021	I97L	C	D	View

Target gene [MX1] related to VISs

DVID	Chromosome	HM	TFBS	Sum of Overlapped Records	Detail
1004513	chr2	43	36	79	View
1004807	chr21	52	16	68	View
1402845	chr21	52	16	68	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MX1 expression and immune infiltrating cell level correlation result in HBV+ samples
MX1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).

> Dataset: LIHC