HBV Target gene Detail Information

> MTSS1 Gene Search Result


Gene Information
Gene Name MTSS1
Gene ID 9788
Gene Full Name MTSS1, I-BAR domain containing
Gene Alias MIM; MIMA; MIMB
Transcripts ENSG00000170873
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID O43312
HGNC ID HGNC:20443
VEGA ID OTTHUMG00000048189
OMIM ID 608486
String ID 9606.ENSP00000322804
PharmGKB ID PA134892011
Target gene [MTSS1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006935 chr8 7 25 32 View
1008553 chr8 3 6 11 20 View
1009334 chr8 6 10 16 View
1013966 chr8 2 2 4 View
1015750 chr8 2 2 View
1015751 chr8 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MTSS1 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MTSS1 expression: Low -> High
Lollipop of MTSS1 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MTSS1 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MTSS1 expression and immune infiltrating cell level correlation result in HBV+ samples
MTSS1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).