HIV Target gene Detail Information

> MTPAP Gene Search Result

Gene Information

Gene Name	MTPAP
Gene ID	55149
Gene Full Name	mitochondrial poly(A) polymerase
Gene Alias	PAPD1; SPAX4; TENT6
Transcripts	ENSG00000107951
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q9NVV4
HGNC ID	HGNC:25532
VEGA ID	OTTHUMG00000017895
OMIM ID	613669
String ID	9606.ENSP00000263063
PharmGKB ID	PA164723192

Target gene [MTPAP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003901	chr10	25	24	3	52	View
4005146	chr10	35			35	View
4008751	chr10	14			14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MTPAP expression and immune infiltrating cell level correlation result in HIV+ samples
MTPAP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).