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HBV Target gene Detail Information

> MTOR Gene Search Result


Gene Information
Gene Name MTOR
Gene ID 2475
Gene Full Name mechanistic target of rapamycin kinase
Gene Alias SKS; FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Transcripts ENSG00000198793
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Vesicles;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID P42345
HGNC ID HGNC:3942
VEGA ID OTTHUMG00000002001
OMIM ID 601231
String ID 9606.ENSP00000354558
Drugbank ID BE0002386
Drug (Cytoscape Annotation) Everolimus
PharmGKB ID PA28360
FDA Approved Drug Everolimus;Temsirolimus
Target gene [MTOR] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008510 chr1 13 5 2 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MTOR expression and immune infiltrating cell level correlation result in HBV+ samples
MTOR expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).