EBV Target gene Detail Information

> MTCL1 Gene Search Result

Gene Information

Gene Name	MTCL1
Gene ID	23255
Gene Full Name	microtubule crosslinking factor 1
Gene Alias	SOGA2; CCDC165; KIAA0802
Transcripts	ENSG00000168502
Virus	EBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y4B5
HGNC ID	HGNC:29121
VEGA ID	OTTHUMG00000131594
OMIM ID	615766
String ID	9606.ENSP00000352927
PharmGKB ID	PA128394616

Target gene [MTCL1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
3000147	chr18	105	2		107	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE100458 (GEO)	Burkitt lymphoma	14	Burkitt lyphoma cell line Akata(EBV+)(2),Burkitt lyphoma cell line Akata(EBV-)(2),Burkitt lyphoma cell line Awia(EBV+)(2),Burkitt lyphoma cell line Awia(EBV-)(2),Burkitt lyphoma cell line Eli(EBV+)(1),Burkitt lyphoma cell line Eli(EBV-)(1),Burkitt lyphoma cell line Mutu(EBV+)(2),Burkitt lyphoma cell line Mutu(EBV-)(2)
GSE42867 (GEO)	Burkitt lymphoma	12	Burkitt lymphoma cell line Awia (EBV+)(12)
GSE12452 (GEO)	Nasopharyngeal carcinoma	41	Nasopharyngeal carcinoma (EBV+)(31), Normal(10)

> Dataset: GSE100458
HeatMap of cell type fractions in all samples	Lollipop of MTCL1 expression and immune infiltrating cell level correlation result in EBV+ samples
MTCL1 expression: Low -> High

> Dataset: GSE42867
HeatMap of cell type fractions in all samples	Lollipop of MTCL1 expression and immune infiltrating cell level correlation result in EBV+ samples
MTCL1 expression: Low -> High

> Dataset: GSE12452
HeatMap of cell type fractions in all samples	Lollipop of MTCL1 expression and immune infiltrating cell level correlation result in EBV+ samples
MTCL1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).