HIV Target gene Detail Information

> MTBP Gene Search Result

Gene Information

Gene Name	MTBP
Gene ID	27085
Gene Full Name	MDM2 binding protein
Gene Alias	MDM2BP
Transcripts	ENSG00000172167
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Nuclear bodies;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96DY7
HGNC ID	HGNC:7417
VEGA ID	OTTHUMG00000165040
OMIM ID	605927
String ID	9606.ENSP00000303398
PharmGKB ID	PA31224

Target gene [MTBP] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003547	chr8	43	16		59	View
4006130	chr8	24	3		27	View
4011523	chr8	4	2		6	View
4016429	chr8				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MTBP expression and immune infiltrating cell level correlation result in HIV+ samples
MTBP expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).